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Left PAK4 depletion or functional inhibition of group II PAKs reduces ERО± protein levels in MCF 7 cells iv lasix side effects In the same context, it is of great importance to highlight that Top2B is of such significance in initiating transcription that even targeted artificial induction of DSB at promoters of the serum inducible genes Fos and Npas4 was found lead to their transcription even in the absence of the inducing signal 141

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